Vaginal and anal fissures. The symptoms include recurrent itching, redness, fissures, and vulva dysuria. Irritable bowel syndrome IBS Irritable bowel syndrome can't be cured with medications or special diets but avoiding individual triggers can help prevent it Throat cancer Risk factors for throat cancer include smoking and heavy alcohol consumption It may be the first indication of a more serious problem such as an area of infection or cancer. Chronic anal fissure, which persists for more than six weeks. Barium tests are used to examine conditions of the digestive tract such as reflux, narrowing or ulceration McGraw-Hill Education; Painkillers and efforts to soften stool, such as through medication or a high-fiber diet, can improve this symptom.